Table 1. Top 20 differentially expressed genes from RNASeq.

Listed are the normalized counts of the top 20 differentially expressed genes with p<0.01, ranked by p value. The 10 genes designated in bold were subsequently validated by qRT-PCR (Fig. 3). Values shown in italics depict decreased expression in the IP3 cell line relative to the parental. ND – not detected, therefore no ratio is calculated.

Gene	Gene name(s)	OVCAR5	OVCAR5IP3	5IP3/parental	OVCAR8	OVCAR8IP3	8IP3/parental
PLAU	urinary-type plasminogen activator, urokinase	51.03	334.11	6.55	16.57	155.89	9.41
KISS1	Kiss-1 metastasis suppressor	31.90	1.16	0.04	39.46	2.57	0.07
TAOK1	serine-threonine protein kinase	2055.71	80.33	0.04	70.24	55.17	0.79
SPOCK1	testican-1 proteoglycan	194.57	12.81	0.07	26.83	3.85	0.14
COL6A3	α3 chain of type VI collagen	4.78	61.70	12.91	1.58	24.38	15.43
SEC11C	signal peptidase complex catalytic subunit	28.71	102.44	3.57	29.20	89.17	3.05
SERPINE2	serine protease inhibitor serpin E2, protease nexin 1	307.80	46.57	0.15	74.97	42.98	0.57
IFI44	interferon induced protein 44	6.38	3.99	0.62	168.89	1.28	0.01
SDPR	serum deprivation response protein, cavin-2	271.12	20.95	0.08	199.67	94.95	0.48
PODXL	podocalyxin-like protein 1	146.72	23.28	0.16	48.93	23.09	0.48
GAL	galanin and GMAP prepropeptide	35.09	9.31	0.27	64.71	12.19	0.19
TENM2	teneurin transmembrane protein 2	ND	8.15	---	ND	49.37	---
FN1	fibronectin 1	17.54	23.29	1.33	21.31	214.91	10.08
TUBB2A	tubulin beta 2A	157.89	18.62	0.12	84.44	47.78	0.57
AMIGO2	adhesion molecule with Ig-Like domain 2	ND	53.55	---	ND	6.41	---
SPINT2	serine peptidase inhibitor kunitz type 2, hepatocyte growth factor activator inhibitor type 2 (HAI-2)	41.47	165.31	3.99	49.72	94.30	1.90
IFI6	interferon inducible protein 6	38.27	13.97	0.37	65.50	13.47	0.21
PSMD2	proteasome 26S subunit non-ATPase-2	244.00	403.95	1.66	247.81	704.38	2.84
IL32	interleukin 32	51.03	2.32	0.05	41.83	14.11	0.34
TGM2	transglutaminase-2	141.94	16.30	0.11	32.36	25.02	0.77