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MB ablation decreases fatty acid oxidation and increases the survival time of p53172H/H mice. A, Kaplan-Meier survival plot of p53172H/H mice with or without MB deletion. Statistical difference by log-rank (Mantel-Cox) test. B, Spectra of cancer types diagnosed by necropsy and histopathology. C, The effect of MB deletion on fatty acid oxidation was measured in thymic lymphocytes using 3H-palmitate as substrate (n = 3). *P < 0.05.
