Table 1.

Differential diagnoses of multiple pyogenic granulomas

	Examination	Dermoscopy	Histopathology
Pyogenic granuloma	Usually single or rarely multiple reddish or skin-colored papulo-nodules	White/red homogenous stuctureless area, white rail lines, ulceration, white collarete	Vascular proliferation in lobular fashion. Fibrous septations, inflammation and edema.
Bacillary angiomatosis	Mutiple reddish or brown papules or subcutaneous lumps Dramatic response after antibiotic therapy	-	Single or multinodular proliferations of capillaries with inflammatory infiltrate. Extracellular deposits of hemotoxylin grain material. Leucocytoclasis seen.
Kaposi's Sarcoma (nodular)	Numerous dome shaped skin colored or erythematous nodular lesions	Bluish reddish coloration, polychromatic rainbow pattern with surface scales and brown clods.	Honey comb like network of blood filled spaces/slits closely associated with spindle cells woven between delicate vascular spaces.
Angio-keratoma	Single or multiple reddish, bluish-black keratoticpapulo-nodules	Red lacunae, dark blue lacunae, whitish veil	Acanthosis, hyperkeratosis, multiple blood-filled ectatic, and congested thin-walled blood vessels in papillary dermis with normal deep dermis and subcutaneous tissue