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. 2020 Aug 20;32(2):71–77. doi: 10.1097/DER.0000000000000666

TABLE 3.

The Performance of Nickel in the Human Maximization Test

Test Substance* Induction/Challenge,† % Positive
Potassium dichromate 2.0/0.25 100%
p-Phenylenediamine 10/0.5 100%
Mercuric chloride 2.0/0.05 92%
Epoxy resin‡ 25/15 84%
Butylglycidyl ether 10/10 79%
Formalin 5.0/1.0 72%
Gold chloride 2.0/0.005 69%
Penicillin G 25/10 58%
Nickel sulfate 10/2.5 48%
Cobaltous sulfate 25/2.5 40%
Mercaptobenzothiazole 25/10 38%
Aniline 20/10 28%
Benzocaine 25/10 19%
Methyl paraben 25/10 4%
Aluminum chloride 25/10 0%
Propylene glycol 25/10 0%

*The example substances have been sampled from Kligman37 with a focus on metal salts.

†These are the percentages of concentrations respectively used for the induction and challenge phases.

‡Composition not specified in the original article.37