Table 4.
Detailed presentation of CYP2C9 genotype, enzyme activity, metabolism type, and the possible effect on drug concentrations.
Number of patients (%) | Genotypes | Enzyme activity; | Metabolism type | Possible effect on drug concentration |
n = 44 (81.48%) | ∗1/∗1; | Fully functional; | Normal metabolizers | Drug concentration will remain in the therapeutic range. |
n = 10 (18.51%) | ∗1/∗2;∗1/∗3; | Decreased; | Intermediate metabolizers | Drug concentration will exceed therapeutic range. |
CYP2C9 = Cytochrome P450 2C9 enzyme.