Table 1. Demographic features and tumor marker and biochemical parameters levels in control, breast cancer, and colon cancer cases (mean± SD).
BMI, body mass index; CA-15.3, cancer antigen 15.3; CA-19.9, cancer antigen 19.9; CEA, carcinoembryonic antigen; NF-κB, nuclear factor kappa-B; sTRAIL, soluble tumour necrosis factor (TNF)-related apoptosis-inducing ligand; TNF-α, tumour necrosis factor-α; IL-6, interleukin 6; PCT, procalcitonin; PTX-3, pentraxin 3; CRP, C-reactive protein. a: vs control; b: vs breast cancer; * < 0.05; ** < 0.01; *** 0.001.
| Control (n:30) | Breast cancer (n:40) | Colon cancer (n:40) | |
|---|---|---|---|
| Age (Year) | 48.97±4.95 | 49.20±7.35 | 49.88±7.21 |
| Sex (F/M) | 15 / 15 | 40 / 0 | 20 / 20 |
| BMI (kg/m2) | 23.49±1.86 | 25.40±2.95a* | 24.57±3.88 |
| CA-15.3 (U/mL) | 10.93±3.27 | 34.54±15.06a*** | 14.92±5.17b*** |
| CA-19.9 (U/mL) | 4.47±2.20 | 7.51±4.08 | 27.91±8.39a***,b*** |
| CEA (ng/mL) | 1.49± 0.63 | 5.83±4.21a** | 6.06±7.13a*** |
| WBC (x109 /L) | 6.65±1.23 | 7.00±1.66 | 7.18±2.02 |
| NF-кB (ng/mL) | 0.37±0.17 | 0.98±0.31a*** | 0.93±0.80a*** |
| sTRAIL (pg/mL) | 58.93±11.98 | 50.95±8.26a** | 49.60±11.51a*** |
| TNF-α (pg/mL) | 1.96±0.62 | 10.79±3.20a*** | 13.39±3.40a***,b*** |
| IL-6 (pg/mL) | 4.97±1.89 | 46.46±23.54a*** | 64.19±20.12a***,b*** |
| PCT (pg/mL) | 12.88±3.35 | 36.02±8.80a*** | 50.54±13.54a***,b*** |
| PTX-3 (pg/mL) | 351.53±99.06 | 1826.25±361.99a*** | 2208.55±450.44a***,b*** |
| CRP (mg/L) | 1.63±0.65 | 4.17±1.55a*** | 4.71±2.38a*** |