FIGURE 5.

The interface between domain III and the chymotrypsin fold of SARS-CoV 3CL^pro. The domain III surface of the active protomer 1UK3_A (a) and G11A monomer (b) are represented, respectively. c and d, the surface of the rest of 1UK3_A and G11A. The gray surface in c represents the N-terminal finger of the other protomer 1UK3_B. The contact residues on the interface are labeled, and the atoms involved in forming hydrogen bonds or salt bridges are colored with oxygen in red and nitrogen in blue.