Figure 4.

Effects of L. zeae LB1 on the resistance to S. typhimurium DT104 infection of C. elegans mutants that are defective in the genes for cell signaling. The life-span of different types of C. elegans mutants, including nsy-1 (A), sek-1 (B), pmk-1 (C), daf-16 (D), age-1 (E), ced-3 (F), and ced-9 (G), responding to DT104 infection were evaluated with or without the pretreatment of L. zeae LB1. All the assays were treated with 10⁸ CFU/ml LB1 or E. coli OP50 (control group) for 18h and then with DT104 for remain days. Comparisons were made between the worms pre-exposed to L. zeae LB1 prior to DT104 infection (LB1 + DT104) and those exposed to DT104 only (DT104). The P value for each comparison is indicated inside of each panel.