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Autophagy inhibition decreased leptin-induced ERK activation in breast cancer cells. Leptin (L) induced ERK phosphorylation (A,B) in both cell lines. Autophagy inhibition with chloroquine (CQ) decreased leptin-induced ERK phosphorylation at 15 min. MEK inhibitor PD0325901 25 nM was used as a positive control. Mean ± SEM; n = 4; p < 0.05. *vs. C; # vs. L.
