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. 2021 Mar 8;11:608842. doi: 10.3389/fonc.2021.608842

Table 4.

Hallmark Pathways enriched in high- and low-risk groups by using GSEA.

ID NES p value p.adjust FDR
HALLMARK_KRAS_SIGNALING_DN −1.909 0.001 0.027 0.018
HALLMARK_MYOGENESIS −2.822 0.001 0.027 0.018
HALLMARK_PANCREAS_BETA_CELLS 1.692 0.004 0.045 0.03
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION −1.55 0.004 0.045 0.03
HALLMARK_MYC_TARGETS_V2 1.722 0.005 0.045 0.03
HALLMARK_SPERMATOGENESIS 2.529 0.009 0.047 0.031
HALLMARK_E2F_TARGETS 4.224 0.012 0.047 0.031
HALLMARK_G2M_CHECKPOINT 3.904 0.012 0.047 0.031
HALLMARK_INTERFERON_GAMMA_RESPONSE 1.679 0.012 0.047 0.031
HALLMARK_MTORC1_SIGNALING 1.524 0.012 0.047 0.031
HALLMARK_MYC_TARGETS_V1 1.971 0.012 0.047 0.031
HALLMARK_MITOTIC_SPINDLE 2.916 0.012 0.047 0.031
HALLMARK_INTERFERON_ALPHA_RESPONSE 1.834 0.012 0.047 0.031
HALLMARK_INFLAMMATORY_RESPONSE 1.268 0.024 0.084 0.055
HALLMARK_ANDROGEN_RESPONSE 1.51 0.025 0.084 0.055
HALLMARK_APICAL_SURFACE −1.518 0.034 0.105 0.069
HALLMARK_ALLOGRAFT_REJECTION 1.248 0.036 0.105 0.069
HALLMARK_P53_PATHWAY −1.331 0.044 0.12 0.079
HALLMARK_IL6_JAK_STAT3_SIGNALING 1.396 0.046 0.12 0.079

GSEA, gene set enrichment analysis; NES, normalized enrichment score; FDR, false discovery rate.