Table 6.
The multivariate analyses of overall survival and progression-free survival according to HMMR protein expression, after adjusting for other potential predictors (n = 70).
| Characteristics | Overall survival | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Clinical stage (I–IIvs. III–IV) | 2.644 (0.966–7.234) | 0.058 | 3.109 (1.157–8.353) | 0.024 |
| Age (≤ 60 vs. >60) | 1.270 (0.600–2.689) | 0.533 | 1.296 (0.635–2.647) | 0.476 |
| Gender (Female vs. Male) | 0.754 (0.076–7.516) | 0.810 | 0.688 (0.071–6.646) | 0.747 |
| Histologic grade (G1 vs. G2/G3) | 1.075 (0.514–2.249) | 0.848 | 1.134 (0.559–2.298) | 0.728 |
| Anatomic site (Oral cavity/Oropharynx/Hypopharynx vs. Larynx) | 2.049 (0.782–5.371) | 0.144 | 1.949 (0.802–4.737) | 0.141 |
| HMMR (Low vs. High) | 2.288 (1.019–5.137) | 0.045 | 2.247 (1.048–4.817) | 0.038 |