Table 1.
Modification of hemodynamic parameters during left anterior descending occlusion and reperfusion.
| Time | HR (bpm) | CO (L/min) | PLV Sys (mmHg) | PLV Dia (mmHg) | PAo Sys (mmHg) | PAo Dia (mmHg) | Pfem Sys (mmHg) | Pfem Dia (mmHg) | PAP Sys (mmHg) | PAP Dia (mmHg) |
|---|---|---|---|---|---|---|---|---|---|---|
| BSL | 74 ± 14 | 5.3 ± 1.1 | 96 ± 8 | 3 ± 6 | 94 ± 6 | 55 ± 6 | 98 ± 20 | 52 ± 14 | 36 ± 5 | 16 ± 4 |
| AMIt0 | 77 ± 14 | 5.1 ± 0.8 | 80 ± 9* | 5 ± 4 | 78 ± 10* | 47 ± 10 | 80 ± 17‡ | 47 ± 14 | 29 ± 6 | 14 ± 4 |
| AMIt80 | 85 ± 18 | 4.7 ± 0.85† | 80 ± 6* | 5 ± 4 | 79 ± 7* | 50 ± 8 | 79 ± 22* | 46 ± 16 | 33 ± 4 | 16 ± 3 |
| REt0 | 87 ± 18 | 4.7 ± 0.64† | 81 ± 7* | 5 ± 4 | 80 ± 8* | 49 ± 9 | 83 ± 22‡ | 47 ± 17 | 33 ± 4 | 16 ± 4 |
| REt60 | 89 ± 17*a | 4.4 ± 0.96‡ | 82 ± 7* | 5 ± 3 | 80 ± 9* | 49 ± 11 | 86 ± 18 | 50 ± 11 | 33 ± 11 | 15 ± 5 |
| PALL value | 0.0001 | 0.0001 | 0.005 | ns | 0.005 | ns | 0.0001 | ns | ns | ns |
BSL, baseline; AMIt0−−t80, acute myocardial infarction at t0 and t80, respectively; REt0−−t60, reperfusion at t0 and t60, respectively; HR, heart rate; PLV Sys and PLV Dia, systolic and diastolic LV pressures, respectively; PAo Sys and PAo Dia, systolic and diastolic aortic pressures, respectively; Pfem Sys and Pfem Dia, systolic and diastolic femoral pressures, respectively; PAP Sys and PAP Dia, systolic and diastolic pulmonary arterial pressures, respectively.
Results from multiple-comparison analysis account for comparison of the different timepoints against BSL. Data are presented as mean ± SD.
p < 0.05;
p < 0.01;
p < 0.0001.
Comparison is significant against AMIt0.