Table 4.
CD – Inflammatory Behavior and No Perianal Disease (B1) (n=90) | CD with Strictures, Fistulas or Perianal Disease (B2, B3 or Bxp) (n=213) | p | |
---|---|---|---|
Age at diagnosis (mean±SD) | 33.3±16.4 | 31.4±13.6 | 0.023* |
Duration of disease (mean±SD) | 7.7±7.5 | 11.8±9.5 | <0.001* |
Female (n, %) | 46 (51.1) | 106 (49.8) | 0.830 |
Smoking habit at diagnosis of CD (n, %) | 18 (20) | 53 (24.9) | 0.209 |
Hospitalization (n, %) | 53 (58.9) | 192 (90.1) | <0.001* |
Salicylates (n, %) | 84 (93.3) | 183 (85.9) | 0.068 |
Corticosteroids (n, %) | 59 (65.6) | 171 (80.3) | 0.006* |
Immunomodulators (n, %) | 47 (52.2) | 190 (89.2) | <0.001* |
Biologics (n, %) | 22 (24.4) | 148 (69.5) | <0.001* |
At least 1 IBD-related surgery (n, %) | 10 (11.1) | 150 (70.4) | <0.001* |
Notes: Quantitative variables: Student’s t-test (normal distribution); categorical variables: χ2 test; *p < 0.05= statistical significance. IBD-related surgery: CD abdominal or perianal procedures due to complications of disease;
Abbreviations: CD, Crohn’s disease; SD, standard deviation; n, number of patients; Bxp, B1, B2, or B3 with perianal disease.