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Schematics of the insulin- and enzyme nanocapsules-loaded microgels. Glucose is catalyzed by enzyme into the gluconic acid which in turn leads to the protonation of –NH2 on the polymer chains. Insulin is ultimately released as a result of the protonation-caused swelling of the microgels. Reprinted with the permission from Ref. 62 Copyright © 2013 American Chemical Society.
