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. 2020 Sep 3;11(3):651–667. doi: 10.1016/j.apsb.2020.08.016

Figure 6.

Figure 6

(a) Schematics of the procedures for preparing CPP/insulin nanoparticle (NP-A) core, HA-coated NPs (NP-B1/B2/B3) and HPMCP coated NP-B (MC-1/2/3). (b) Blood glucose level-time curves of diabetic rats after oral administration of MC-1/2/3 (80 IU/kg). ∗P < 0.05 vs. NP-B1, #P < 0.05 vs. NP-B2. (c) Serum insulin level of diabetic rats following oral administration of MC-1/2/3 (80 IU/kg). Subcutaneous injection of insulin solution (5 IU/kg) is the control. Data are means ± SD (n = 6). Reprinted with the permission from Ref. 106 Copyright © 2018 Royal Society of Chemistry.