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. 2020 Nov 28;11(3):727–737. doi: 10.1016/j.apsb.2020.11.021

Figure 5.

Figure 5

Other factors are involved in CAR activation-induced hepatomegaly and liver regeneration. (A) The mRNA level of other related genes in wild-type mice treated by TCPOBOP or corn oil for 5 or 10 days. (B) The mRNA level of other related genes in wild-type or Yap–/– mice. (C) The protein levels of C-Myc, FOXM1 and MET were upregulated after treated by TCPOBOP for 5 or 10 days. (D) The protein levels of C-Myc, FOXM1, CTNNB1 and MET were upregulated after treated by TCPOBOP in Yap−/− mice. (E) Quantification of Western blot results in wild-type mice. (F) Quantification of Western blot results in Yap−/− mice. Data are presented as mean±SD, n = 5; ∗P<0.05, ∗∗P<0.01, ∗∗∗P<0.001, ∗∗∗∗P<0.0001, significantly different to control; Student's t test.