Table 5.
Proposed Technologies Under Development for SARS-CoV-2 Diagnosis
| Technology | Manufacturer | Capturing Agent | Target | Reference |
|---|---|---|---|---|
| Aptamer based detection | Laboratory developed | Anti-RBD aptamer | RBD | [282] |
| DNA aptamer | N | [223] | ||
| RNA aptamer | RNA transcript | [224] | ||
| Molecular Imprinting Technology | Laboratory developed | Plastic monoclonal type antibody | Spike protein | [283] |
| Microarray | Laboratory developed | SARS-CoV 2 proteome | IgG + IgM | [227] |
| Coronavirus + respiratory virus antigen | IgG/IgA | [229] | ||
| Biosensor | Laboratory developed | Cell-based biosensor + Spike S1 antibody | S1 | [232] |
| FET + Anti-spike protein | Spike protein | [231] | ||
| P-FAB + anti-N protein | N protein | [233] | ||
| Surface-enhanced Raman scattering (SERS) | Laboratory developed | SN-SERS+ ACE2 | RBD | [235] |
Abbreviations: FET, field effect transistor; P-FAB, plasmonic fiber optic absorbance biosensor; ACE 2, angiotensin-converting enzyme-2.