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. 2021 Mar 8;12:605372. doi: 10.3389/fneur.2021.605372

Table 4.

Ordinal regression model analysis of influencing factors of PVWMH classifications.

Predictor PVWMH Fazekas grade
Coefficient Standard error Z value P-value OR 95%CI for OR
Age 0.085 0.010 73.770 <0.01 1.089 1.067–1.110
Hypertension 0.479 0.193 6.143 0.013 1.614 1.105–2.358
Diabetes mellitus 0.457 0.195 5.502 0.019 1.579 1.078–2.314
Atrial fibrillation 0.214 0.503 0.181 0.671 1.239 0.462–3.320
LI 1.640 0.192 73.072 <0.01 5.155 3.540–7.508
LP-PLA2 <200* −1.356 0.276 3.102 0.019 0.258 0.119–0.520
LP-PLA2 200–223* −1.187 0.421 7.949 0.005 0.305 0.134–0.696
Cr −0.003 0.004 0.408 0.523 0.997 0.989–1.006
Hcy 0.010 0.012 0.778 0.378 1.010 0.987–1.034
H-CRP −0.002 0.007 0.107 0.743 0.998 0.984–1.011

LI, lacunar infarction; Cr, creatinine; H-CRP, high C-reactive protein; Hcy, homocysteine; Lp-PLA2, lipoprotein-associated phospholipase A2;

*

LP-PLA2 >232.00 ug/L served as control.