Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 8;11:642030. doi: 10.3389/fonc.2021.642030

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Hong, Ye, Wang, Fang, Wang, Luo, Liu, Liu, Liu, Zhao and Chang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of miR-21-3p on malignant HCC phenotypes could be partly reversed via SMAD7 overexpression. (A) Flow cytometry was performed to analyze the apoptotic index of Huh-7 (a) and Hep-G2 (b) cells after transfection. Cells were co-stained with Annexin FITC/PI; Annexin FITC+/PI- cells that stained green were considered as being in early apoptosis. Normal, late-stage apoptotic and necrotic cells are shown in yellow, red and purple, respectively. Three independent experiments were performed. Data are shown as mean ± SD. (B) Transwell assay was performed to detect the migration (a, b) and invasion (c, d) in Huh-7 and Hep-G2 cells separately after transfection. *P < 0.05, **P < 0.01; ***P < 0.001.