FIGURE 4.

The bioinformatic analysis of differentially expressed proteins. (A) Volcano plots showing the differentially expressed proteins in lmwCAFS and MT‐lmwCAFS. (B) The molecular function analysis of differentially expressed proteins in lmwCAFS and MT‐lmwCAFS shown in the chord plot. (C) Volcano plots showing the differentially expressed proteins in lmwCAFS‐treated PC‐3 cells/MT‐lmwCAFS‐treated PC‐3 cells. (D) Biological process analysis of the differentially expressed proteins in lmwCAFS‐treated PC‐3 cells/MT‐lmwCAFS‐treated PC‐3 cells. (E) KEGG pathway analysis of the differentially expressed proteins in lmwCAFS‐treated PC‐3 cells/MT‐lmwCAFS‐treated PC‐3 cells shown in the chord plot. The red fonts represent proteins belonging to the FoxO pathway. (F) Protein interactions in the FoxO pathway. In the chord plot, proteins are linked with their assigned terms via ribbons. Red‐to‐blue rectangles next to selected proteins represent their logFC. GO molecular function or KEGG pathway terms are arranged from top to bottom according to their significance