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. 2021 Mar 8;10(7):2470–2481. doi: 10.1002/cam4.3830

FIGURE 5.

FIGURE 5

SENP1 is a target of MCM3AP‐AS1/miR‐193a‐5p axis. (A) The potential mRNA targets of MCM3AP‐AS1 and miR‐193a‐5p were predicted by starBase database and targetScan database, respectively. B‐D, The mRNA and protein levels of SENP1 were determined in MCM3AP‐AS1‐depleted or miR‐193a‐5p overexpression CRC cells by RT‐qPCR (B, C) and western blot (D), respectively. (E) The relative luciferase activity of SENP1‐3’UTR‐WT or SENP1‐3’UTR‐MUT cotransfected with miR‐193a‐5p mimics were determined by dual luciferase reporter assays. *p < 0.05, **p < 0.01.