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. 2021 Mar 10;10(7):2380–2395. doi: 10.1002/cam4.3833

FIGURE 5.

FIGURE 5

Model depicting the structured tumor‐immune microenvironment in patients afflicted with cervical disease. As demonstrated, we started by analyzing flow cytometry results and gene expression profiles to discover the temporal order of cancer hallmarks and evolving immune response in cervical carcinogenesis, then put forth the potential immunotherapeutic markers targeting susceptible patients. HSIL, high‐grade squamous intraepithelial lesions; LSIL, low‐grade squamous intraepithelial lesions; SCC, squamous cell carcinoma