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. 2021 Mar 2;10(7):2396–2422. doi: 10.1002/cam4.3660

TABLE 1.

Sources of natural compounds with anticancer activity

Category Natural compounds Main Source References
Plants Ginsenosides Ginseng [11, 12]
Camptothecin (CPT) Camptotheca acuminata [14]
Curcumin (CUR) Turmeric [22, 23]
β‐elemene (β‐ELE) Turmeric [26]
Gambogic (GA) Han's Geng Huang resin [28, 29]
Tanshinone Salvia miltiorrhiza [32, 34]
Licorice chalcone (LIC) Licorice [35, 37, 38, 39, 40, 41]
Triptolide (TPL) Tripterygium wilfordii [42]
Emodin (ED) Rhubarb [44]
Berberine (BBR) Coptis chinensis [48]
Epigallocatechin gallate (EGCG) Green tea [52, 53, 54]
Resveratrol (RSV) Grapes, red wine and peanuts [56]
Artemisinin Artemisinin annua [59]
Silybin Silymarin [62]
Cinnamon Cinnamon [70, 71]
Animals Astaxanthin (ATX) Shrimp, salmon, crab, red yeast and other marine animals [73]
Melittin Bee venom [77, 78]
Snake venom Snake [81, 82, 83]
Scorpion venoms Scorpion [85, 86, 87]
Microorganisms Doxorubicin (Dox) Penicillium Streptomyces [21, 89]
Staurosporine (STS) Streptomyces and other actinomycetes [92]
Epothilone myxobacteria and Cysticercus cellulosus [95]
Mitomycin C (MMC) Streptococcus Kaisers [21]
Marine organisms Psammaplin A (PSA) Psammaplysilla sponge [104]
Ecteinascidin−743 (ET−743) Ecteinascidia turbinata [108]
Halichondrin B Halichondria okadai, Axinella, Phakellia, and Lissodendoryx [112]