TABLE 1.
Category | Natural compounds | Main Source | References |
---|---|---|---|
Plants | Ginsenosides | Ginseng | [11, 12] |
Camptothecin (CPT) | Camptotheca acuminata | [14] | |
Curcumin (CUR) | Turmeric | [22, 23] | |
β‐elemene (β‐ELE) | Turmeric | [26] | |
Gambogic (GA) | Han's Geng Huang resin | [28, 29] | |
Tanshinone | Salvia miltiorrhiza | [32, 34] | |
Licorice chalcone (LIC) | Licorice | [35, 37, 38, 39, 40, 41] | |
Triptolide (TPL) | Tripterygium wilfordii | [42] | |
Emodin (ED) | Rhubarb | [44] | |
Berberine (BBR) | Coptis chinensis | [48] | |
Epigallocatechin gallate (EGCG) | Green tea | [52, 53, 54] | |
Resveratrol (RSV) | Grapes, red wine and peanuts | [56] | |
Artemisinin | Artemisinin annua | [59] | |
Silybin | Silymarin | [62] | |
Cinnamon | Cinnamon | [70, 71] | |
Animals | Astaxanthin (ATX) | Shrimp, salmon, crab, red yeast and other marine animals | [73] |
Melittin | Bee venom | [77, 78] | |
Snake venom | Snake | [81, 82, 83] | |
Scorpion venoms | Scorpion | [85, 86, 87] | |
Microorganisms | Doxorubicin (Dox) | Penicillium Streptomyces | [21, 89] |
Staurosporine (STS) | Streptomyces and other actinomycetes | [92] | |
Epothilone | myxobacteria and Cysticercus cellulosus | [95] | |
Mitomycin C (MMC) | Streptococcus Kaisers | [21] | |
Marine organisms | Psammaplin A (PSA) | Psammaplysilla sponge | [104] |
Ecteinascidin−743 (ET−743) | Ecteinascidia turbinata | [108] | |
Halichondrin B | Halichondria okadai, Axinella, Phakellia, and Lissodendoryx | [112] |