TABLE 1.

Correlation between the clinicopathologic characteristics and CFL1 expression in hepatocellular carcinoma

			CFL1 expression
Characteristics		n = 100	Low (n = 50)	High (n = 50)	p
Age (year)	<50	34	15	19	0.398
	≥50	66	35	31
Gender	Male	84	40	44	0.275
	Female	16	10	6
HBV infection	Absent	22	16	6	0.016*
	Present	78	34	44
Serum AFP level (ng/ml)	<20	34	20	14	0.205
	≥20	66	30	36
Tumour size (cm)	<5	38	25	13	0.013*
	≥5	62	25	37
Tumour number	1	77	43	34	0.033*
	≥2	23	7	16
Cirrhosis	Absent	30	19	11	0.081
	Present	70	31	39
Venous infiltration	Absent	58	38	20	<0.001*
	Present	42	12	30
Edmondson‐Steiner grading	I+II	63	34	29	0.300
	III+IV	37	16	21
TNM stage	I+II	82	47	35	0.002*
	III+IV	18	3	15

Abbreviations: AFP, alpha‐fetoprotein; HBV, hepatitis B virus; TNM, tumour‐node‐metastasis.

^*Indicates statistically significant.