TABLE 4.

Differentially abundant microbiota before and after probiotics treatment.

Strain	Level	Microbe	Mean		T-test P-value (<0.1)
			Before	After
CACC517 (B. longum)	Phylum	k__Bacteria; p__Fusobacteria	0.023	0.008	0.078
	Class	k__Bacteria; p__Firmicutes; c__Erysipelotrichi	0.038	0.089	0.036
	Class	k__Bacteria; p__Fusobacteria; c__Fusobacteriia	0.023	0.008	0.078
	Order	k__Bacteria; p__Firmicutes; c__Erysipelotrichi; o__Erysipelotrichales	0.038	0.089	0.036
	Order	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales	0.023	0.008	0.079
	Family	k__Bacteria; p__Firmicutes; c__Erysipelotrichi; o__Erysipelotrichales; f__Erysipelotrichaceae	0.039	0.091	0.033
	Family	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales; f__Fusobacteriaceae	0.023	0.009	0.075
	Genus	k__Bacteria; p__Firmicutes; c__Clostridia; o__Clostridiales; f__Clostridiaceae; g__Clostridium	0.001	0.020	0.079
	Genus	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales; f__Fusobacteriaceae; g__Fusobacterium	0.023	0.009	0.076
CACC566 (L. paracasei)	Phylum	k__Bacteria; p__Bacteroidetes	0.100	0.229	0.023
	Class	k__Bacteria; p__Bacteroidetes; c__Bacteroidia	0.100	0.229	0.023
	Order	k__Bacteria; p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales	0.100	0.229	0.023
	Family	k__Bacteria; p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Bacteroidaceae	0.088	0.198	0.095
	Genus	k__Bacteria; p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Bacteroidaceae; g__Bacteroides	0.088	0.200	0.096
CACC558 (L. plantarum)	Phylum	k__Bacteria; p__Fusobacteria	0.011	0.000	0.073
	Class	k__Bacteria; p__Firmicutes; c__Bacilli	0.130	0.232	0.085
	Class	k__Bacteria; p__Actinobacteria; c__Coriobacteriia	0.032	0.000	0.045
	Class	k__Bacteria; p__Firmicutes; c__Erysipelotrichi	0.049	0.014	0.033
	Class	k__Bacteria; p__Fusobacteria; c__Fusobacteriia	0.012	0.000	0.072
	Order	k__Bacteria; p__Actinobacteria; c__Coriobacteriia; o__Coriobacteriales	0.033	0.000	0.045
	Order	k__Bacteria; p__Firmicutes; c__Erysipelotrichi; o__Erysipelotrichales	0.049	0.015	0.034
	Order	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales	0.012	0.000	0.072
	Order	k__Bacteria; p__Firmicutes; c__Bacilli; o__Lactobacillales	0.116	0.229	0.090
	Family	k__Bacteria; p__Firmicutes; c__Clostridia; o__Clostridiales; f__Clostridiaceae	0.179	0.061	0.072
	Family	k__Bacteria; p__Actinobacteria; c__Coriobacteriia; o__Coriobacteriales; f__Coriobacteriaceae	0.033	0.000	0.045
	Family	k__Bacteria; p__Firmicutes; c__Erysipelotrichi; o__Erysipelotrichales; f__Erysipelotrichaceae	0.049	0.015	0.034
	Family	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales; f__Fusobacteriaceae	0.012	0.000	0.072
	Family	k__Bacteria; p__Firmicutes; c__Clostridia; o__Clostridiales; f__Veillonellaceae	0.004	0.000	0.023
	Genus	k__Bacteria; p__Actinobacteria; c__Coriobacteriia; o__Coriobacteriales; f__Coriobacteriaceae; g__Collinsella	0.027	0.000	0.083
	Genus	k__Bacteria; p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales; f__Fusobacteriaceae; g__Fusobacterium	0.012	0.000	0.070
CACC537 (P. acidilactici)	Family	k__Bacteria; p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Porphyromonadaceae	0.003	0.001	0.096
	Genus	k__Bacteria; p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Porphyromonadaceae; g__Parabacteroides	0.003	0.001	0.096