Figure 1.

Suppressed tumor growth of E0771 tumor cells in AhRR Tg mice. (A) Tumor volume of 10-week-old control AhRR Tg mice and littermate wt mice (n = 8 for each group) following subcutaneous injection of 5.0 × 10⁵ E0771 breast cancer cells into the mammary fat pad. (B) After 24 h mice were i.p. injected with 10 μg/kg TCDD (blue lines). Mean ± SEM are shown and two-tailed Student's t-test was used. ^aSignificantly higher than AhRR Tg Ctrl mice, ^bsignificantly higher than wt Ctrl or TCDD-treated AhRR Tg mice (p < 0.01).