Table 3.
Association between serum IL-6 levels (as exposure) and severity of COVID-19 (as the outcome) in infected patients with and without MAFLD at hospital admission.
| Total (n = 167) | Without MAFLD (n = 121) | With MAFLD (n = 46) | P for interaction | ||||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | ||
| Unadjusted Model | 1.06 (1.03–1.09) | <0.001 | 1.04 (1.00–1.07) | 0.028 | 1.11 (1.04–1.19) | 0.003 | 0.055 |
| Adjusted Model 1 | 1.05 (1.02–1.09) | <0.001 | 1.03 (0.99–1.06) | 0.086 | 1.12 (1.04–1.21) | 0.004 | 0.022 |
| Adjusted Model 2 | 1.04 (1.02–1.09) | 0.002 | 1.02 (0.99–1.05) | 0.091 | 1.14 (1.05–1.23) | 0.002 | 0.008 |
Data are expressed as odds ratio (OR) and 95% confidence intervals as tested by univariable (unadjusted) and multivariable (adjusted) logistic regression analysis.
Adjusted Model 1: adjusted for age and sex
Adjusted Model 2: adjusted for age, sex, overweight/obesity, type 2 diabetes, and hypertension.
Bold values represent statistical significant P values.