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. 2021 Mar 8;12:650922. doi: 10.3389/fendo.2021.650922

Table 1.

Baseline characteristics between survival group and death group.

Characteristic Totals (n=322) Survivals (n=242) Deaths (n=80) P
Age (year-old) 60.51 ± 16.24 59.62 ± 16.41 63.21 ± 15.50 0.086a
Sex (F/M) 110/212 76/166 34/46 0.078b
BMI (Kg/m2) 24.27 ± 4.53 24.27 ± 4.50 24.26 ± 4.65 0.982a
HR (bpm) 86 ± 22 87 ± 22 85 ± 22 0.411a
SBP (mmHg) 125 ± 22 128 ± 23 118 ± 17 0.000a
DBP (mmHg) 78 ± 15 80 ± 16 74 ± 12 0.000a
ALT (U/L) 26.70 (17.73, 46.68) 31.30 (21.80, 49.70) 24.25 (15.83, 58.13) 0.165c
AST (U/L) 29.30 (22.90, 44.18) 30.70 (24.00, 43.90) 27.40 (21.70, 46.35) 0.034c
ALB (g/L) 37.36 ± 4.67 37.71 ± 4.67 36.27 ± 4.52 0.020a
Scr (umol/L) 87.10 (72.05, 109.95) 89.60 (76.00, 110.70) 96.95 (78.63, 137.88) 0.004c
BUN (mmol/L) 7.19 (5.82, 9.54) 7.28 (6.17, 8.71) 8.49 (6.14, 10.90) 0.000c
UA (mmol/L) 473.0 (382.0, 582.0) 479.0 (388.0, 576.0) 526.5 (446.0, 748.0) 0.029c
CysC (mg/L) 1.31 (1.12, 1.63) 1.31 (1.10, 1.57) 1.52 (1.23, 1.77) 0.001c
K (mmol/L) 3.99 ± 0.51 3.96 ± 0.48 4.09 ± 0.56 0.042a
Na (mmol/L) 139.76 ± 4.09 140.19 ± 3.81 138.49 ± 4.62 0.004a
Ca (mmol/L) 2.25 ± 0.14 2.25 ± 0.14 2.25 ± 0.14 0.993a
HB (g/L) 133.08 ± 20.81 135.24 ± 20.08 126.55 ± 21.70 0.001a
RDW (%) 14.95 ± 4.78 14.75 ± 5.35 15.54 ± 2.29 0.205a
D-dimer (mg/L) 0.75 (0.30, 1.72) 0.59 (0.29, 1.58) 0.94 (0.31, 2.84) 0.001c
NT-proBNP (ng/L) 1979 (1176, 4315) 1775 (1205, 2933) 2626 (1688, 6615) 0.000c
cTnT (ng/L) 61.80 ± 387.34 45.82 ± 295.11 101.74 ± 556.69 0.380a
CK-MB (U/L) 35.34 ± 122.90 36.27 ± 139.96 32.98 ± 61.23 0.869a
TTE
LVDd (mm) 61.53 ± 12.51 61.35 ± 11.96 62.08 ± 14.12 0.661a
LVDs (mm) 48.85 ± 14.01 48.67 ± 13.52 49.39 ± 15.53 0.697a
PASP (mmHg) 42.0 (31.5, 53.0) 40.0 (31.0, 48.0) 48.0 (30.5, 60.5) 0.005c
LVEF% 42.50 ± 14.81 42.43 ± 14.57 42.71 ± 15.62 0.885a
NYHA 0.228b
II (n%) 48 (14.9) 40 (16.5) 8 (10.0)
III (n%) 181 (56.2) 137 (56.6) 44 (55.0)
IV (n%) 93 (28.9) 65 (26.9) 28 (35.0)
Comorbidities
IHD (n%) 76 (23.6) 55 (22.7) 21 (26.3) 0.545b
Cardiomyopathy (n%) 130 (40.4) 101 (41.7) 29 (36.3) 0.431b
VHD (n%) 86 (26.7) 63 (26.0) 23 (28.8) 0.663b
PHD (n%) 23 (7.1) 17 (7.0) 6 (7.5) 1.000b
Atrial fibrillation (n%) 122 (37.9) 94 (38.8) 28 (35.0) 0.596b
CHD (n%) 10 (3.1) 6 (2.5) 4 (5.0) 0.273b
HTN (n%) 162 (50.3) 125 (51.7) 37 (46.3) 0.440b
DM (n%) 77 (23.9) 55 (22.7) 22 (27.5) 0.450b
Pulmonary Infection (n%) 66 (20.5) 48 (19.8) 18 (22.5) 0.633b
Renal dysfunction (n%) 20 (6.2) 10 (4.1) 10 (12.5) 0.013b
Thyroid Dysfunction 0.763b
Hyperthyroidism(n%) 7 (2.2) 6 (2.5) 1 (1.3)
Hypothyroidism(n%) 1 (0.3) 1 (0.4) 0 (0)
Smoking (n%) 121 (37.6) 98 (40.5) 23 (28.8) 0.064b

F, Female; M, Male; BMI, Body Mass Index; HR, Heart Rate; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; ALB, Albumin; Scr, Serum Creatinine; BUN, Blood Urea Nitrogen; UA, Uric Acid; CysC, CystatinC; HB, Hemoglobin; RDW, Red blood cell Distribution Width; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; cTnT, cardiac troponin T; CK-MB, Creatine kinase-MB; LVDd, Left Ventricular Diastolic Dimension; LVDs, Left Ventricular Systolic Dimension; PASP, Pulmonary Artery Systolic Pressure; LVEF, Left Ventricular Ejection Fraction; IHD, Ischemic Heart Disease; VHD, Valvular Heart Disease; PHD, Pulmonary Heart Disease; CHD; Congenital Heart Disease; HTN, Hypertension; DM, Diabetes Mellitus.

aCalculated by unpaired t-test; bcalculated by Chi-square test; ccalculated by rank sum test.