. 2021 Mar 8;12:650922. doi: 10.3389/fendo.2021.650922

Table 3.

Comparison of the SNP genotype under different genetic models between the death and survival groups.

Gene	SNPs	Group	Dominance		HR (95%CI)	χ2	P	Recessive		HR (95%CI)	χ2	P
Gene	SNPs	Group	Mm + mm	MM	HR (95%CI)	χ2	P	mm	MM + Mm	HR (95%CI)	χ2	P
TERC	rs12696304	D	53(0.671)	26(0.329)	2.29 (1.34–3.90)	9.53	0.002	12(0.152)	67(0.848)	1.89 (0.88–4.03)	2.74	0.133
	G/C	S	114(0.471)	128(0.529)	2.29 (1.34–3.90)	9.53	0.002	21(0.087)	221(0.913)	1.89 (0.88–4.03)	2.74	0.133
	rs10936599	D	67(0.838)	13(0.163)	2.84 (1.48–5.44)	10.5	0.001	23(0.287)	57(0.713)	1.98 (1.10–3.57)	5.26	0.035
	T/C	S	156(0.645)	86(0.355)	2.84 (1.48–5.44)	10.5	0.001	41(0.169)	201(0.831)	1.98 (1.10–3.57)	5.26	0.035
	rs1317082	D	67(0.838)	13(0.163)	2.89 (1.51–5.54)	10.9	0.001	23(0.287)	57(0.713)	2.10 (1.16–3.80)	6.17	0.021
	G/A	S	155(0.640)	87(0.360)	2.89 (1.51–5.54)	10.9	0.001	39(0.161)	203(0.839)	2.10 (1.16–3.80)	6.17	0.021
	rs10936601	D	53(0.663)	27(0.338)	2.20 (1.30–3.74)	8.83	0.003	13(0.163)	67(0.838)	2.04 (0.97–4.30)	3.65	0.062
	T/C	S	114(0.471)	128(0.529)	2.20 (1.30–3.74)	8.83	0.003	21(0.087)	221(0.913)	2.04 (0.97–4.30)	3.65	0.062
	rs16847897	D	54(0.675)	26(0.325)	1.23 (0.72–2.10)	0.57	0.503	13(0.163)	67(0.838)	1.15 (0.57–2.30)	0.15	0.718
	C/G	S	152(0.628)	90(0.372)	1.23 (0.72–2.10)	0.57	0.503	35(0.145)	207(0.855)	1.15 (0.57–2.30)	0.15	0.718
TERT	rs7726159	D	53(0.663)	27(0.338)	1.03 (0.60–1.75)	0.01	1.000	21(0.263)	59(0.738)	1.97 (1.07–3.63)	4.89	0.03
	C/A	S	159(0.657)	83(0.343)	1.03 (0.60–1.75)	0.01	1.000	37(0.153)	205(0.847)	1.97 (1.07–3.63)	4.89	0.03
	rs2736100	D	56(0.700)	24(0.300)	1.11 (0.64–1.92)	0.14	0.782	21(0.263)	59(0.738)	1.75 (0.96–3.18)	3.35	0.073
	A/C	S	164(0.678)	78(0.322)	1.11 (0.64–1.92)	0.14	0.782	41(0.169)	201(0.831)	1.75 (0.96–3.18)	3.35	0.073

SNP, single nucleotide polymorphism; HR, hazard ratio; D, death group; S, survival group; M, major allele; m, minor allele.

The major/minor alleles were G/C (rs12696304), T/C (rs10936599), G/A (rs1317082), T/C (rs10936601), C/G (rs7726159), C/A (rs1317082) and A/C (rs2736100) respectively.