Table 4.
COX regression analysis of different genetic models.
| Genotype | χ2 | HR (95%CI) | P | ||
|---|---|---|---|---|---|
| rs12696304 | Codominance | GG | – | 1.0(ref.) | – |
| CC | 8.16 | 3.35(1.46–7.66) | 0.004 | ||
| CG | 8.96 | 2.65(1.40–5.02) | 0.003 | ||
| Dominance | GG | – | 1.0(ref.) | – | |
| CC+CG | 10.82 | 2.79(1.52–5.16) | 0.001 | ||
| Recessive | GG+CG | – | 1.0(ref.) | – | |
| CC | – | – | 0.071 | ||
| rs10936599 | Codominance | TT | – | 1.0(ref.) | – |
| CC | 11.1 | 4.98(1.94–12.79) | 0.001 | ||
| TC | 6.95 | 3.27(1.36–7.89) | 0.008 | ||
| Dominance | TT | – | 1.0(ref.) | – | |
| CC+TC | 9.05 | 3.72(1.58–8.74) | 0.003 | ||
| Recessive | TT+TC | – | 1.0(ref.) | – | |
| CC | 5.9 | 2.07(1.15–3.72) | 0.015 | ||
| rs1317082 | Codominance | GG | – | 1.0(ref.) | – |
| AA | 12.39 | 5.35(2.10–13.63) | 0 | ||
| GA | 6.17 | 3.05(1.27–7.37) | 0.013 | ||
| Dominance | GG | – | 1.0(ref.) | – | |
| AA+GA | 8.76 | 3.63(1.55–8.51) | 0.003 | ||
| Recessive | GG+GA | – | 1.0(ref.) | – | |
| AA | 8.35 | 2.35(1.32–4.18) | 0.004 | ||
| rs10936601 | Codominance | TT | – | 1.0(ref.) | – |
| CC | 6.58 | 3.07(1.30–7.23) | 0.01 | ||
| TC | 10.81 | 3.01(1.56–5.79) | 0.001 | ||
| Dominance | TT | – | 1.0(ref.) | – | |
| CC+TC | 11.91 | 3.02(1.61–5.66) | 0.001 | ||
| Recessive | TT+TC | – | 1.0(ref.) | – | |
| CC | – | – | 0.16 | ||
| rs7726159 | Codominance | CC | – | 1.0(ref.) | – |
| AA | 6.82 | 2.69(1.28–5.65) | 0.009 | ||
| CA | 0.68 | 1.32(0.69–2.53) | 0.409 | ||
| Dominance | CC | – | 1.0(ref.) | – | |
| AA + CA | – | – | 0.12 | ||
| Recessive | CC + CA | – | 1.0(ref.) | – | |
| AA | 4.47 | 1.96(1.05–3.65) | 0.034 | ||
Adjusted with systolic and diastolic blood pressure, aspartate aminotransferase, albumin, Serum creatinine, blood urea nitrogen, uric acid, cystatinC, serum potassium, serum sodium, hemoglobin, D-Dimer, NT-proBNP, pulmonary artery systolic pressure, and comorbidity of renal dysfunction.