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. 2021 Mar 18;2(1):100386. doi: 10.1016/j.xpro.2021.100386

Figure 6.

Figure 6

Profiling bioenergetics of intestine-derived organoids

(A and B) OCR (A) and ECAR (B) measurements of a mitochondrial stress test of doxycycline-inducible shFoxo1/3 mouse small intestinal organoids treated with or without doxycycline for 36 h (mean of 5 technical replicates ± SEM). Figure reprinted with permission from Ludikhuize et al. (2020).

(C and D) ECAR (A) and OCR (B) measurements of a glycolysis stress test of two different patient-derived colorectal cancer organoids (P16t and P19bt) (mean of 5 technical replicates ± SEM).