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. 2021 Mar 5;8:606197. doi: 10.3389/fvets.2021.606197

Table 5.

The DNA methylation (%) changes at inflamed modulated gene promoters after the mixture treatment of inflamed CPEK cells.

CPEK
Time 4 h 8 h
Inflamed Yes
Mix No Yes No Yes
ccl2 Site 1 8.33 ± 0.44 8.18 ± 0.24 5.15 ± 4.58 19.23 ± 9.23
Site 2 81.20 ± 2.00 82.68 ± 0.88 81.53 ± 0.60 59.00 ± 37.03
Site 3 73.81 ± 1.27 73.84 ± 1.08 65.18 ± 13.94 67.03 ± 17.83
Site 4 90.98 ± 0.83 91.76 ± 0.48 83.20 ± 15.53 81.54 ± 20.69
Site 5 91.23 ± 0.60 91.83 ± 1.70 86.71 ± 6.95 79.70 ± 16.44
Average 69.11 ± 0.65 69.66 ± 0.75 64.35 ± 11.55 61.30 ± 17.46
ccl17 Site 1 97.69 ± 2.33 99.33 ± 1.16 98.82 ± 1.11 100.00 ± 0.00
Site 2 88.55 ± 3.47 90.36 ± 2.33 92.02 ± 7.03 95.82 ± 3.66
Site 3 81.44 ± 1.87 75.22 ± 2.35a 78.09 ± 1.63 78.53 ± 7.99
Site 4 98.47 ± 1.80 100.00 ± 0.00 98.31 ± 2.92 92.56 ± 12.89
Site 5 88.78 ± 2.76 84.80 ± 7.61 88.41 ± 8.85 84.95 ± 4.45
Average 90.99 ± 0.93 89.94 ± 2.01 91.15 ± 4.05 90.37 ± 0.91
tslp Site 1 95.06 ± 0.43 96.43 ± 0.44a 95.83 ± 1.79 96.85 ± 1.59
Site 2 93.97 ± 0.54 94.82 ± 0.58 96,05 ± 2.42 96.05 ± 2.42
Site 3 80.29 ± 0.94 81.21 ± 2.30 83.17 ± 2.78 83.17 ± 2.78
Site 4 85.38 ± 1.02 83.79 ± 4.17 87.72 ± 3.80 87.72 ± 3.80
Site 5 77.05 ± 1.10 71.25 ± 11.77 83.38 ± 9.04 83.38 ± 9.04
Site 6 92.01 ± 0.89 93.44 ± 0.35 93.66 ± 1.58 93.66 ± 1.58
Average 87.29 ± 0.31 86.82 ± 1.91 89.96 ± 1.83 90.14 ± 3.14
a

p < 0.05 vs. yes inflamed 4 h no mix 4 h.