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. 2021 Mar 5;8:606197. doi: 10.3389/fvets.2021.606197

Table 6.

The DNA methylation (%) changes at inflamed modulated gene promoters after the mixture treatment of inflamed DH82 cells.

DH82
Time 4 h 8 h
Inflamed Yes
Mix No Yes No Yes
ccl2 Site 1 81.20 ± 6.39 87.95 ± 1.80 77.91 ± 5.97 77.43 ± 1.06b
Site 2 79.52 ± 6.16 91.46 ± 1.19a 87.31 ± 4.53 85.29 ± 5.13
Site 3 90.20 ± 4.96 94.93 ± 0.88 90.41 ± 5.32 93.13 ± 3.28
Site 4 92.49 ± 3.56 97.06 ± 0.85 96.06 ± 0.38 96.34 ± 0.39
Site 5 93.51 ± 6.96 95.62 ± 1.52 92.15 ± 4.97 94.60 ± 1.71
Site 6 76.32 ± 2.95 76.90 ± 3.31 73.88 ± 4.11 84.39 ± 3.86b,c
Average 85.54 ± 3.69 90.65 ± 0.79 86.29 ± 3.30 88.53 ± 0.97
ccl17 Site 1 100.00 ± 0.00 99.38 ± 0.88 99.25 ± 1.30 100.00 ± 0.00
Site 2 93.46 ± 11.32 82.98 ± 15.70 81.25 ± 8.22 74.22 ± 2.79
Site 3 84.20 ± 2.40 81.70 ± 5.50 76.27 ± 1.33a 84.17 ± 0.97c
Site 4 99.95 ± 0.09 98.76 ± 2.15 100.00 ± 0.00 98.29 ± 2.20
Site 5 89.11 ± 1.75 89.12 ± 2.19 86.79 ± 1.81 89.60 ± 1.54
Average 93.34 ± 2.94 90.39 ± 5.18 88.71 ± 2.05 89.25 ± 2, 38
il31ra Site 1 44.88 ± 1.34 49.25 ± 4.57 50.30 ± 3.27 48.46 ± 0.59
Site 2 43.07 ± 1.29 47.21 ± 2.20a 47.46 ± 3.59 45.49 ± 1.92
Average 43.98 ± 0.86 48.23 ± 3.38 48.88 ± 3.38 46.98 ± 1.10
a

p < 0.05 vs. yes inflamed 4 h no mix 4 h;

b

p < 0.05 vs. yes inflamed 4 h yes mix 4 h;

c

p < 0.05 vs. yes inflamed 8 h no mix 8 h.