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Summary of gene mutations in MSO patients.
| Study | Cancer type | Gene mutations | Protein |
|---|---|---|---|
| Coyne et al. (26) | FVPTC | NRAS codon 61C > A | gln → lys |
| Wolff et al. (27) | FVPTC | BRAF exon 601A > G | lys → glu K601E |
| Luo et al. (28) | PTC | KRAS codon12 G > T | gly → val |
| Seifert et al. (29) | FVPTC | None | None |
| Tsukada et al. (30) | FTC | None | None |
| Gild et al. (31) | FTC | None | None |
| Ma et al. (13) | FVPTC | KITc.1588G > Ac.1621A > C | p.V530I p.M541L |
| Flavin et al. (32) | PTC | BRAF codon 600T > A | T1799A val → glu |
