Table 3.
Clinical characteristics of patients used for the RT-dPCR analysis of the (A) TB/OD signature and (B) the TB/LTBI signature.
| Group | TB HIV+ | TB HIV– | OD HIV+ | OD HIV– |
|---|---|---|---|---|
| A | ||||
| Number | 10 | 10 | 10 | 10 |
| Age (years) mean (range) | 32.3 (26.3–48.0) |
31.9 (18.1–60.7) |
34.3 (24.9–53.1) |
41.1 (19.1–68.1) |
| Sex (male, %) | 50 | 50 | 20 | 30 |
| BMI (kg/m2) mean (range) | 19.5 (16.8–22.9) |
19.4 (15.3–24.2)a |
24.3 (18.0–39.3) |
22.1 (17.2–33.0)b |
| CD4 count (mm3) mean (range) | 222.5 (29.2–646.0) |
NA | 252.8 (19.3–838.0) |
NA |
| Anti-retroviral therapy (%) | 0 | NA | 50 | NA |
| aOne missing value; bThree missing values. | ||||
| Group | TB HIV+ | TB HIV– | LTBI HIV+ | LTBI HIV– |
| B | ||||
| Number | 10 | 10 | 10 | 10 |
| Age (years) mean (range) | 32.6 (24.2–47.5) |
39.7 (290.0–59.8) |
36.7 (22.5–53.2)a |
31.9 (18.9–59.2) |
| Sex (male, %) | 60 | 50 | 20 | 40 |
| BMI (kg/m2) mean (range) | 20.3 (16.8–25.1) |
20.4 (14.3–29.4) |
21.6 (16.5–25.8)a |
21.9 (17.7–29.4) |
| CD4 count (mm3) mean (range) | 226.0 (29.2–345.0) |
NA | 466.1 (227.0–958.0)b |
NA |
| Anti-retroviral therapy (%) | 0 | NA | 0 | NA |
| TST induration (mm) mean (range) | ND | ND | 22.9 (4.0–50.0)a |
16.6 (10.0–21.0) |
a
One missing value;
b
Two missing values.
BMI, body mass index; NA, not applicable; ND, not done; TST, tuberculin skin test; LTBI, Latent TB infection; OD, other diseases.