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. 2020 Jul 8;13(4):395–399. doi: 10.1136/neurintsurg-2020-016118

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Inflammatory panel volcano plot illustrating proteomic log2 fold changes in NormalizedProtein eXpression (NPX) in intracranial blood compared with systemic blood. Labeled proteins include C-C motif chemokine 19 (CCL19), C-C motif chemokine 20 (CCL20), fibroblast growth factor 21 (FGF21), transforming growth factor alfa (TGF-α), C-C motif chemokine 23 (CCL23), and axin-1 (AXIN1). Proteins with negative fold change are located to the left of the vertical line and indicate higher expression in systemic blood. Proteins located above the horizontal line are significant (p<0.05). Changes in AXIN1 were found to be non-significant after controlling for the false discovery rate.