Table 4:

Suggested age of last screening episode for colorectal cancer based on the number needed to screen to gain one life year, by sex, comorbidity status and prior screening with biennial faecal immunochemical testing or colonoscopy. The faecal immunochemical test had a positivity of 7.5% (23 μg Hb/g faeces).

Screening Historya / Comorbidity statusb	Females				Males
	No	Low	Mod	Sev	No	Low	Mod	Sev
Perfect Prior Screening with FIT	78	72	72	66	76	76	72	66
Most Prior Screening with FIT	84	82	78	70	80	80	76	70
Reasonable Prior Screening with FIT	86	84	82	76	82	82	78	74
Some Prior Screening with FIT	88	86	86	80	84	84	82	78
No Prior Screening	90	90	90	86	88	88	86	82
Colonoscopy 10 years prior	74	68	66	<66	73	72	69	<66
Colonoscopy 15 years prior	83	76	74	68	80	78	75	66

Abbreviations: FIT = faecal immunochemical test; Mod = moderate; Sev = severe

Key: Blue – stop screening later than recommended in guidelines; Green – stop screening in line with guidelines; Red – stop screening earlier than recommended in guidelines

^a.Detailed descriptions of screening history are found in Table 1. In brief, perfect prior screening assumes 100% attendance in prior screening rounds, most prior screening assumes 75% attendance in prior screening rounds, reasonable prior screening assumes 50% attendance in prior screening rounds, some prior screening assumes 25% attendance in prior screening rounds and no prior screening assumes no attendance in prior screening rounds. For colonoscopy we assume screening occurred 10 and 15 years prior to the investigated stop-age.

^b.Detailed descriptions of comorbid conditions are found in Table 2. In brief there are four categories: no comorbidity, low comorbidity, moderate comorbidity and severe comorbidity