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. 2020 Jun 26;117(4):1202–1216. doi: 10.1093/cvr/cvaa164

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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.

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Changes of cell–cell interactions in hypertension. (A) Changes of cell–cell interaction pairs involving growth factors among non-immune vascular cells of SHR-AA and SHR-MA with WKY counterparts as control. (B) Changes of cell–cell interaction pairs involving proinflammatory molecules with non-immune cells as broadcasting cells in SHR-AA with WKY counterparts as control. (C) Changes of cell–cell interaction pairs involving growth factors and proinflammatory molecules with immune cells as broadcasting cells in SHR-AA with WKY counterparts as control. Cells before the underscore contribute to the interaction pair as ligand cells, and cells after are receptor cells. AA, aortic artery; EC, endothelial cell; MA, mesenteric artery; MSC, mesenchymal stromal cell; SHR, spontaneously hypertensive rats; SMC, smooth muscle cell; TGFb, transforming growth factor beta; WKY, Wistar Kyoto.