Table 2.
Nomogram | mpMRI Model AUC (95% CI) | Systematic TRUS Biopsy |
Targeted TRUS Biopsy |
||||
---|---|---|---|---|---|---|---|
Nomogram AUC (95% CI) | Nomogram + mpMRI AUC (95% CI) | p Value | Nomogram AUC (95% CI) | Nomogram + mpMRI AUC (95% CI) | p Value | ||
MSKCC: | |||||||
Organ confined disease | 0.78 (0.72e0.83) | 0.70 (0.64e0.76) | 0.80 (0.75e0.85) | <0.001* | 0.77 (0.73e0.84) | 0.82 (0.76e0.87) | 0.046* |
Extraprostatic extension | 0.78 (0.71e0.82) | 0.70 (0.63e0.77) | 0.80 (0.74e0.85) | 0.003* | 0.77 (0.73e0.83) | 0.82 (0.75e0.87) | 0.045* |
Seminal vesicle invasion | 0.86 (0.75e0.92) | 0.81 (0.71e0.88) | 0.90 (0.83e0.96) | 0.011* | 0.76 (0.67e0.86) | 0.85 (0.72e0.93) | 0.065 |
Lymph node invasion | 0.87 (0.77e0.92) | 0.82 (0.70e0.89) | 0.88 (0.83e0.94) | 0.120 | 0.88 (0.84e0.95) | 0.94 (0.91e0.97) | 0.023* |
Partin: | |||||||
Organ confined disease | 0.78 (0.72e0.83) | 0.73 (0.67e0.78) | 0.81 (0.75e0.86) | 0.001* | 0.78 (0.74e0.84) | 0.83 (0.76e0.88) | 0.030* |
Extraprostatic extension | 0.78 (0.71e0.82) | 0.66 (0.59e0.71) | 0.80 (0.73e0.83) | <0.001* | 0.67 (0.61e0.75) | 0.79 (0.73e0.85) | 0.003* |
Seminal vesicle invasion | 0.86 (0.75e0.92) | 0.80 (0.71e0.89) | 0.88 (0.82e0.96) | 0.022* | 0.83 (0.69e0.88) | 0.87 (0.77e0.96) | 0.452 |
Lymph node invasion | 0.87 (0.77e0.92) | 0.85 (0.68e0.88) | 0.91 (0.85e0.96) | 0.0710 | 0.89 (0.84e0.97) | 0.93 (0.86e0.97) | 0.085 |
Significant at p <0.05.