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. 2021 Mar 8;21(5):466. doi: 10.3892/etm.2021.9897

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Copyright: © Chong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Expression levels of NLRP3 and caspase-1 mRNA in BEAS-2 cells. The mRNA expression levels of (A) NLRP3 and (B) caspase-1 in the LPS- and leptin-pretreated BEAS-2 cells were all significantly increased compared with those in the control group (P<0.01). After mitoQ treatment, the expression levels were significantly decreased (P<0.01). Values are expressed as the mean ± standard error of the mean of 3 samples analyzed in triplicate. ^*P<0.01 vs. control group; ^∆P<0.01 vs. DMSO group; ^#P<0.01 vs. LPS group; ^&P<0.01 vs. leptin group. NLRP3, NOD-, LRR- and pyrin domain-containing protein 3; mitoQ, mitoquinone; LPS, lipopolysaccharide.