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. 2021 Mar 19;20:15347354211002662. doi: 10.1177/15347354211002662

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Distribution of digoxin and digitoxin on cell cycle in SKOV-3 cells. Cells were exposed to (A) digoxin and (B) digitoxin at indicated concentrations for 24, 48, and 72 hours. Flow cytometric analysis was used to detect DNA contents. Percentages of cells in the G0/G1 phase were presented. (C) The percentage of hypodiploid cells incubated with digitoxin at indicated concentrations for 24, 48, and 72 hours were measured under the sub-G1 fraction.

Each value represents mean ± SEM of 3 independent experiments.

**P < .01 as compared with control group.