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. 2021 Mar 22;23:31. doi: 10.1186/s12968-021-00722-7

Table 4.

The ROC analysis in the prediction of the upper tertile of N-terminal pro-brain natriuretic peptide (NTproBNP > 2000 pg/ml)

PVL quantification AUC (SE) p Optimal value Sensitivity (%) Specificity (%) PPV (%) NPV (%)
TEE: PVL circumference (%) 0.746 (0.116) 0.03 21 62 87 71 82
CMR: PVL volume (ml) 0.791 (0.09) 0.001 30 100 70 57 100
CMR: PVL regurgitant fraction (%) 0.79 (0.08 0.001 27,5 100 65 53 100

AUC area under the curve, CMR cardiovascular magnetic resonance, NPV negative prediction value, PVL paravalvular leak, PPV positive prediction value, ROC receiver operating characteristics, SE standard error, TEE transesophageal echocardiography