. 2021 Jan 5;10(2):146–153. doi: 10.1530/EC-20-0435
This work is licensed under a Table 2.
Cycle characteristics and results based on E2/M2 ratio cutoff of 204.
| Variable | E2/M2 ≤ 204, n = 150 | E2/M2 > 204, n = 234 | P-value |
|---|---|---|---|
| Age, years | 34.3 ± 6.1 | 36.6 ± 5.6 | 0.002 |
| Basal FSH (IU/L) | 8.9 ± 3.1 | 8.7 ± 2.9 | NS |
| Basal LH (IU/L) | 5.7 ± 2.3 | 6.1 ± 2.8 | NS |
| Basal E2 (pg/L) (median 25–75%) | 45 (30–119) | 42 (28–78) | NS |
| Basal Progesterone (ng/L) | 0.3 (0.1–0.7) | 0.3 (0.15–0.6) | NS |
| BMI (kg/m2) | 26.2 ± 6.1 | 25.6 ± 5.3 | NS |
| Endometrial thickness (mm) | 9.7 ± 2.3 | 9.6 ± 2.2 | NS |
| Protocol % | P = 0.90 | ||
| Agonist | 38 (28.4%) | 66 (29.6%) | |
| Antagonist | 96 (71.6%) | 157 (70.4%) | |
| Total days of stimulation | 10.1 ± 2.6 | 9.9 ± 2.8 | NS |
| Total gonadotropin dose (iu) | 2070 ± 1200 | 2525 ± 1448 | 0.02 |
| E2 concentration at hCG (pg/L) | 1270 ± 689 | 1529 ± 786 | 0.001 |
| Number oocytes/cycle | 10.8 ± 5.4 | 7.7 ± 2.8 | 0.0001 |
| Number M2/cycle | 9.4 ± 5.1 | 5.3 ± 3.4 | 0.0001 |
| Normal fertilizations/cycle | 6.6 ± 3.7 | 4.1 ± 2.4 | 0.0001 |
| Transferred embryos | 1.8 ± 0.7 | 1.8 ± 0.7 | NS |
| Number of embryos to freeze | 3.2 ± 1.9 | 2.5 ± 1.8 | 0.007 |
| Grade (mean) | 1.8 ± 0.6 | 1.9 ± 0.6 | 0.005 |
| KID score (mean) | 3.3 ± 1.6 | 3.3 ± 1.6 | NS |
| ESHRE score (mean) | 1.6 ± 1.1 | 1.4 ± 1.1 | 0.005 |
| KID 4–5 (%) | 56.7 | 56.4 | NS |
| ESHRE 2–3 (%) | 53.9 | 49.2 | 0.038 |
| Pregnancy outcome/transfer (%) | |||
| Biochemical pregnancy | 45.3 | 34 | 0.032 |
| Clinical | 45.3 | 32.3 | 0.013 |
| Miscarriage rate (%) | 13/150 = 8.6 | 36/234 = 15.3 | 0.05 |
| Live birth rate/transfer (%) | 36.7 | 18.7 | 0.0001 |