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Altered CBF/FCS ratios in POAG patients compared with NCs after including GMV as a covariate (GRF-corrected voxel P value < 0.001 and cluster P value <0.05). The warm and cool colors denote significantly increased and decreased CBF/FCS ratio, respectively, in POAG patients. CBF: cerebral blood flow; FCS: functional connectivity strength; GMV: gray matter volume; POAG: primary open-angle glaucoma; NCs: normal controls; GRF: Gaussian random field.
