Figure 2.

Gal3 administration significantly improves post-ischemic functional recovery. (a–d) Treatment of Gal3 at the time of reperfusion significantly improved the post-ischemic motor function recovery compared with control saline-treated group at day1 and day3 after MCAO and reperfusion. Rats were tested by an investigator blinded to the study group (a). Rotarod test that measures the motor coordination and motor learning indicated by the latency time to fall from a cylinder rotating at 8 r/min. *P<0.05. (b) Adhesive removal test that measures the time taken by rats to remove small adhesive tapes from forepaws. *P<0.05, compared with control rats. (c) Time taken to cross the beam in the beam walk test on days 1 and 3 of reperfusion following transient MCAO. *P<0.05, compared with control rats. (d) Number of foot faults during the beam walk test on days 1 and 3 of reperfusion following transient MCAO (N=10). *P<0.05, compared with control rats.