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. 2020 Jun 17;41(4):857–873. doi: 10.1177/0271678X20931137

Figure 6.

Figure 6.

Gal3 increases phos-AKT and decreased the levels of phos-ERK1/2, and caspase-3 in neuronal cells exposed to in vitro ischemia/oxygen glucose deprivation. (Aa) The expressions of phos-Akt were increased in Gal3-treated cells compared to untreated control cells. Total-Akt remained unchanged in both groups. (Ab) Quantitation of total and phos-Akt levels. *P<0.05. (Ba) The expressions of phos-ERK1/2 were decreased in Gal3-treated cells compared to untreated control cells. Total-ERK1/2 remained unchanged in both groups. (Bb) Quantitation of total and phos-ERK1/2 levels. *P < 0.05. (Ca) Gal3 significantly decreased the levels of cleaved caspase-3 in Gal3-treated cells compared to untreated control cells. (Cb) Quantitation of cleaved caspase-3 levels. *P < 0.05. Representative Western blot and analysis are shown for untreated and Gal3-treated neuronal cells (N=3).The results were normalized to internal control protein actin.