Table 2.
6-OHDA | 20 µg QA | 40 µg QA | |
---|---|---|---|
[11C]UCB-J PET imaging, SUV | 6.2 (2.52) | 31.0 (8.16) | 49.6 (6.72) |
[11C]UCB-J PET imaging, VT | 39.3 (7.98) | 55.1 (5.59) | |
[11C]UCB-J PET imaging, VT, PBIF | 8.46 (2.30) | 37.8 (8.00) | 54.6 (7.02) |
[3H]UCB-J autoradiography | 38.4 (8.03) | 52.5 (3.69) |
Note: Mean unilateral striatal loss (% of contralateral) detected by [11C]UCB-J PET imaging and [3H]UCB-J autoradiography in animal models of disease (6-hyroxydopamine (6-OHDA), quinolinic acid (QA). Values are presented as mean (SD).