Summary statements
| • THs have effects that are exerted through TRs but through noncanonical pathways, such as effects on triglyceride levels and some cardiovascular functions. |
| • THs may also exert effects that occur through non-TRmediated pathways, such as modification of cancer growth. |
| • More research is needed examining the effects of THs that may operate by noncanonical and non-TR-mediated pathways (e.g., cancer progression). |