Axial images in a 59-year-old woman with a 50-mm invasive ductal carcinoma in the right breast. A, T2-weighted image without fat saturation shows a necrotic mass in the right breast and a normal contralateral breast. B, Multiplexed sensitivity-encoding (MUSE) diffusion-weighted image (b value, 800 sec/mm2) in the same slice as A depicting region of interest (ROI) positioning for quality parameters. C, D, Apparent diffusion coefficient (ADC) color maps derived from multishot MUSE diffusion-weighted imaging shows ROI placement. Note the ROI placement within the “darkest” part of the solid component of this necrotic mass in, C. The ROI of the healthy fibroglandular tissue is delineated in, D. The color bar in, C, and, D, indicates the ADC value range in × 10−6 mm2/sec. ADC values obtained from the ROI in, B: mean, 912.8 × 10−6 mm2/sec; minimum, 92 × 10−6 mm2/sec; maximum, 1846 × 10−6 mm2/sec; ROI area, 59.37 mm2. The ROI values in, C: mean, 2043 × 10−6 mm2/sec; minimum, 1133 × 10−6 mm2/sec; maximum, 2868 × 10−6 mm2/sec; ROI area, 52.5 mm2.