Table 3.
Intraoperative data and outcome of patients (mean±standard deviation, number, percentage)
| Variables | Vasopressin group (n=97) | Control group (n=97) | P | |
|---|---|---|---|---|
| Number of fibroids | 1 | 53 | 48 | 0.565 |
| 2 | 29 | 37 | 0.288 | |
| 3 | 15 | 12 | 0.678 | |
| Duration of anesthesia (min) | 105.30±24.45 | 113.70±29.40 | 0.031 | |
| Duration of surgery (min) | 93.10±17.38 | 99.19±20.25 | 0.025 | |
| Amount of blood loss (ml) | Intraoperative | 615.20±58.70 | 690.50±77.63 | 0.001 |
| Postoperative | 152.30±47.28 | 174.70±58.40 | 0.003 | |
| Blood transfusion | Number of patients | 15 (15.46%) | 29 (29.89%) | 0.025 |
| Number of P-RBC (units) | 1.18±0.57 | 1.90±0.85 | 0.001 | |
| Haemoglobin (g/dl) | 11.48±1.25 | 11.23±1.17 | 0.152 | |
| Fluids transfusion | Crystalloids (ml) | 2540.80±520.34 | 2760.95±570.52 | 0.031 |
| Hesteril 6% (ml) | 496.90±55.70 | 515. 10±60.42 | 0.029 | |
| ECG rhythm changes | Bradycardia (HR <60-50bpm) | 17 (17.52%) | 5 (5.15%) | 0.012 |
| Severe bradycardia (HR <40-30 bpm) | 4 (4.12%) | - | 0.129 | |
| Tachycardia (HR >100 bpm) | 9 (9.27%) | 4 (4.12%) | 0.250 | |
| Atrial extrasystole | 12 (12.37%) | 3 (3.09%) | 0.033 | |
| Ventricular extrasystole | 4 (4.12%) | - | 0.129 | |
| Atropine | Number of patients | 17 (17.52%) | 5 (5.15%) | 0.012 |
| Dose (mg) | 0.99±0.43 | 0.54±0.10 | 0.001 | |
| Hypertension (SAP ≥20% above baseline) | 17 (17.52%) | 4 (4.12%) | 0.005 | |
| Hypotension (SAP ≤20% below baseline) | 9 (9.27%) | 3 (3.09%) | 0.136 | |
| Arterial oxygen saturation (SPO2) (%) | 99.20±021 | 99.18±0.22 | 0.992 | |
| Partial pressure of carbon dioxide (PaCO2)(mmHg) | 35.73±3.25 | 35.54±3.42 | 0.692 | |
| Troponin I (ng/ml) | 0.41±0.06 | 0.40±0.08 | 0.325 | |
| Myocardial infarction | - | - | ||
| Pulmonary oedema | - | - | ||
| Congestive heart failure | - | - | ||
| Cardiac arrest | - | |||
| Mortality | - | - | ||
*P<0.05 significant comparison between the two groups. SAP : Systolic arterial blood pressure; HR : Heart rate. P-RBC : Packed- red blood cells; ECG:Electrocardiogram